Showing posts with label is. Show all posts
Showing posts with label is. Show all posts
Sunday, March 22, 2015
Why is it difficult to follow a diet
Whether a diet to lose weight, improve your cholesterol levels, due to food allergy, because you have diabetes, or for any other reason, it is never easy to follow. The Daily reports that the physician researchers studied, dissected these difficulties to understand and perhaps around more easily.
Why give up on you on a diet?
You started a diet and you do arrive. You move away in you want. Yes but why do not you get? Twenty people were interviewed during a study to try to rank their reasons to abandon his plan. Here there was a regime for high cholesterol, but it is possible that these same reasons also exist in the case of different diets and just as important to health.
4 reasons to abandon a plan
Four reasons were identified: A difficult relationship between doctor and patient "I do not believe what my doctor," for example, one participant in the study. Maybe doctors should care more about how their message across to the people they follow! Perhaps they should put the conviction, as if a doctor wants to lose weight while someone is overweight himself, it will be much less credible. Or, if he dares to consider that this diet is easy and obvious, which is never the case ??
The second reason why a diet is to interrupt a diminished perception of his own health problems. "After all, Im not so sick" or even "cholesterol, this is not really a disease." The problem that requires you to go on a diet you ultimately not seem that bad. So the investment you are going to put in this diet is very limit. A context Social Responsibility The social context can, too, make you leave your side regime. Eat, it is not just food. It is also a social act, a moment of conviviality and if you must eat apart, eat differently, refuse what they serve you, your morale can drop severely. This feeling of making voluntary social gap can be very difficult to bear and that is a major stumbling block on which a plan may fail. A common dietary pattern that must abandoner the food model you are used is being challenged by your plan. You are forced to change things that you are attached by tradition, habit, positive feelings. Behavior that has always been part of you must be abandoned and it is sometimes very difficult. For example, "I am a cheese region, I do not see myself stopping completely" ?? "The chips, it reminds me of my grandmother who was me every Sunday ?? "And give up these foods that are like food toys, foods that carry with them emotional values is painful. These four elements are factors involved in the brief stop, total abandonment, or just with the ups and downs in the monitoring of a plan. There are others, of course. But already you honestly ask the question "what really prevents me from following this diet? "Allows you to maybe take action. Instead of just saying "its too difficult," dissect these reasons help to cope better, rather than feeling guilty without being able to successfully act an important diet for your health.
Its a bit the principle of a task to do. If it is huge, you give up immediately. If you split it into small tasks, you are doing them one by one and you have a chance to finally achieve your big project. Similarly here, if you act on each opposing force to your diet, one after the other, you significantly increase your chances to get to hold him.
Saturday, March 21, 2015
How the addiction to air conditioning is wrong to diet
The heat forces your body to burn more calories.
This is an almost natural way to lose weight, as long as you balance your diet and not drinking anything.
When thermo ...
The human body must always remain at a temperature around 37 ° C regardless of the outside temperature, not necessarily as -10 ° C and + 30 ° C.
For this, a phenomena battery permanently place there to produce heat (thermogenesis is) or to lose: the thermolysis.
The internal heat comes from all the work that make the cells to produce the energy we need by oxidizing carbohydrates, fats and proteins. The slightest movement of product, the digestive system too, especially when he works thoroughly: you inevitably feel after a heavy meal, too heavy.
As for the loss of internal heat, it is mainly through the evaporation of sweat: the water that comes out of all the pores turns to steam and it refreshes.
This balance between the two is called thermoregulation: its part of basic metabolism and it uses a lot of calories.
When it is hot, the system goes into high gear, resulting in an additional expenditure of calories. If you are not a (an) addict air conditioning, heat forces you, whether you like it or not, increase your energy expenditure: this is one way to lose weight.
Provided you do not eat no matter how!
Oil: the trap salads and crudités
When the thermometer rises, we feel like salads and raw vegetables as raclette bourguignon or beef. What is a beneficial reflex vegetables are rich in water and this, one has a great need.
But who says salads and crudités said dressing for seasoning. And the most important part of the dressing, this is oil. Gold thereof, whether olive, canola, nut, sunflower etc. is always composed of pure lipids. Result: 90 calories on average per tablespoon.
It does not pay thoughtlessly oil in the bowl, you put a measuring cap or it is measured with a dessert spoon. And extends the dressing with a natural fruit juice (not sweet!): Orange, for example, grated carrots or other rawness.
For variety, salad dressings made with yogurt or cottage cheese: they contain a lot less fat, calories and therefore more they are rich in water. The remoulade takes planning very well with white cheese and mustard, it is even more refreshing! Cucumber, it marries yoghurt and herbs.
Thus lightened, these salads bring less fat (which are stored on the buttocks and thighs) are more digestible and suddenly, provide less internal heat. This benefits!
Soup, soup, soup!
To make more chic, say of gazpacho, cold velvety. But the principle is the same: raw or cooked vegetables and mixed.
Soups advantage: lots of water, fiber, vitamins, minerals and salts no (or almost no) cooking to do.
Vegetables (peas, lettuce, radishes, zucchini, etc.) for a velvety are cooked in 5 minutes in a pressure cooker. A helping hand mixer then and presto! it folded. Just let it cool, put in the freezer for 15 minutes although the refresh and its ready to be served.
Gazpacho is the only tomatoes or other vegetables, possibly a little bread, mixed, scented and elongated ice.
No need to add fat in these or those velvety gazpacho: the flavors of the vegetables are sufficient in themselves. And thus they provide few calories.
Cold meats and fish
Cook a chicken or roast beef or roast veal or a big fish in the oven.
Certainly, you do not really want when its 35 ° C in your kitchen, but its only a bad time to go (and do not forget that this heat makes you spend energy!).
But then youll have cold meat and fish that accompany your vegetable salads.
The following meals will be even easier to prepare, all in the most absolute lightness.
Dairy products instead of cheese
In times of great heat, the cheeses are not practical or appealing they drip, sweat, feel strong.
While a good yogurt or cottage cheese from cows milk or goats just out of the fridge, its absolutely delicious.
They are mixed in peaches, apricots, strawberries cut into pieces.
No need to add sugar, fruits contain it all. And thus has great light desserts, delicious and refreshing.
Sodas: in the closet!
Unfortunately, if your fridge is stocked with sodas, it is urgent to store them elsewhere. And this for the good of your family.
A teenager who made sport easily need 2 or 3 liters of fluid a day. If these are brought by the sodas which are archi sweet is the insured cat nutrition.
In addition, soft drink quenches less than water. The sensation of thirst comes much faster.
Fill the water bottle fridge.
If you hear screaming, prepare large pots of sweet little lemonade or water with a little bit of mint syrup or grenadine: it will not be pure water, it will have a little color and sweet flavor and it will be less harmful than sodas.
If the heat lasts long enough, thats probably a good opportunity to them (you?) To detoxify those damn sugary drinks!
Do not drink ice but cool or warm
Since you are sweating more than usual, you logically need a lot more water.
When you swallow a glass and is well chilled, your stomach is agitated in every direction to warm. And produces internal heat you do not need.
In addition, the cold amazes your taste buds and it interfere with the signals sent to your brain. You have, at the moment, you feel refreshed but in fact you do not really have your water quota.
Run water from the tap, fill in your glass and add an ice cube if it insists on staying warm, which is not nice, you désaltérerez much better.
And think of mint tea! Glossy but not warm, not sweet (or very slightly). Thus it is drinking in the Maghreb countries where it is warm.
Save water ice house
Make ice tea with mint, adding in each one or two drops of peppermint alcohol. When you suçoterez them in the day you will have a pleasant feeling of freshness in the mouth.
If you have mussels ad hoc sticks, prepare ice water for the whole family. Mix with water or skim milk with a little mint syrup, strawberry, grenadine, pour into molds and put them in the freezer for 3 hours. It will be fewer calories than ice cream or sorbet trade.
Death is Truth The only Truth
We are living in the age of technology where every thing is in the form of 1(one) and 0(zero). If 1 is everything then 0 is nothing. If 1 is life , 0 is death. Usually people dont like to talk much about death. Do u know why ? Its the fear of death. Nobody ever want to die, or let his near ones die. Even thinking about our death or death of a closed one makes us uncomfortable. Its normal. Its true for everybody. Life in itself is a struggle for existence.
Can death be explained ?
Death is not a very simple phenomena. Its a constant process that starts from our birth and finishes with our body, which we call death. First we will discuss it as a biological concept. Till we are in a mothers womb we are getting life. Our body organs are formed and new cell and tissues are formed. After we are born, the wear and tear starts on our body. Some cells die and body generates new cells. But the process of generation of new cells is higher till we are fully grown into a man or woman. It remains balanced till a certain age. But after some time the process of generation of new cells becomes slower than death rate of cells. Here we are not just talking about cells and tissues of outer body but also of the inner organs. Our immune system also starts to degrade. Combination of these negative features becomes the reason for various diseases. All diseases occur due to mis-functioning of our vital organs. For example diabetes occur due to mis-functioning of Pancreas, Blood pressure occur because our blood cant control the cholesterol level and elasticity of blood vessels is also degraded. So in the end when one of our vital organs is degraded to the extent that it cant work, then our body dies. Usually we call it death when our heart stops beating or our breathing stops.Death is Truth
If we talk with a positive attitude then life is truth. But what do we call positive ? We only call positive that is good for us. But is it correct to to say positive to those things which are good for us. According to me thuth is that which is the beginning. Beginning of human body is just a part of sequence of steps. But truth is that beginning of all things is zero. Universe started from a zero and in the end every thing will be zero again. That means zero is truth. Our life also starts from a zero and also ends in a zero. Which means zero (death) is truth.Philosophy about Death
According to a number of religions, life is a never ending process. Our body is a part of it. Truth is our soul, which can never die. Our body dies because it has certain limitation of time. It cant remain healthy after certain amount of time and thus our body have to die. But soul travels from one body to another and get new birth.
That was the religious philosophy, but it can also be explained in a scientific manner. Life continues in different forms. It doesnt need a soul to there. Our body is composed of different elements present in nature. When we die, either our body is cremated or burnt according to the religion that we follow. But thing remains same our body got mixed with soil, water and air. All these things produces life in new forms. It may be in the form of trees or insects. You might not like it if i say that you would be insect after death, so lets say you will be a tree. Fruits grow on tree. Humans, Birds and various animals eat those fruits and vitamins and minerals present in those fruits help them grow their body. Thus our human body helped in development of various forms of life. Thus life continues.
You can also assume it like an ice cube. Suppose you are an ice cube and when you are poured in a glass of water, your death process starts. You might think that you are going to die. But you are dissolving in the form from which you were generated. Just your state is changing from solid to liquid. When the ice cube is fully dissolved it mixes with that water in the glass. Now if you want to extract that same cube again, its impossible as the molecules of that ice cube are mixed into the complete complete glass of water.
I hope that my explanation of death will help you in understanding death in a better way as its nothing to fear about. Its a part of journey and its the only truth.
Your comments are most welcome. It might also help me in improving my knowledge.
A dangerous regime what is it and why
Spring is the season when all sorts of schemes to flourish lose weight quickly before the summer.
All these RGV (High Speed Plan) are dangerous, all make the bed of obesity and some may put your health at risk.
What for? And how to safely evacuate the pounds of winter.
1 kg of body fat = 8000 calories
Losing weight very quickly spring temptation
Slimming and regrossir
Losing weight slowly and wisely
1 kg of body fat = 8000 calories
To lose 1 kg of this fat ugly housed on the thighs and belly, install an energy deficit of about 8,000 calories.
Female energy requirements are on average 2000 calories a day.
With a balanced diet providing, for example, 1400 calories, you get to a daily 600 calorie deficit.
Theoretically, you have to evacuate the pound of fat calories to 8000 in 13 to 14 days. When there is 3 kilos to eliminate, thats 14 x 3 = 42 days, about 1 ½ months.
If there are 5, then we arrive at 14 x 5 = 70 days, or a little over 2 months. What is reasonable.
If the diet (obviously unbalanced) only gives you 800 calories per day, the deficit is 1200 calories. So a kilo of fat must be evacuated much faster, in about one week.
Now thats the theory. It works pretty much if youve never done before weight loss diet.
It does not work if you drag a history of dieting followed by weight regain because your body remembers that he was deprived of energy and he defends himself by jealously guarding his store of fat. This is the basis of the famous yo-yo pounds mounted and so difficult to identify.
Everyone knows that. But that does not stop - alas! - The periodic madness Plans High Speed.
Losing weight very quickly spring temptation
The attraction for a system that melts the 3 or 5 kg in less than a month is irresistible.
Especially since a girlfriend and just shirk its kilos you taunting sporting a flat-to-home TV and thighs tapered skinny jeans, accented by narrow boots belly as she lost weight for calves.
She swallowed only (optional): soup (cabbage preferably) or pineapple or grapefruit or other exotic fruits, or proteins (chicken breast, surimi or to dilute mixtures in water), or she made the dissociated diet, lemon diet or Atkins or Tahiti, or that of a celebrity fashion etc. The list is here.
The girlfriend still features a bit from its hiding with terracotta and agrees that during the term of this plan while she was a breath of a jackal. But given the outcome, its worth it.
You will look on the Internet and you find, of course, a crowd of enthusiastic testimonials on forums and / or sites that are promoting one of these plans. Sounds great ... despite the prospect of breath.
Why is it dangerous?
· Because all these RGV (High Speed Plan) make you lose first protein.
Indeed, when your body is deprived of energy, it will scan the first in protein because they are the ones who mobilize immediately to provide well before the fat.
And that is really serious. Proteins make up all your tissues, not just muscle but also those of your heart, your liver, your digestive tract, in short, all your organs. So here they are terribly vulnerable. And with you, of course! Cardiac arrest due to RVG does exist.
· Because they do not give you a good quota of vitamins, minerals and essential fatty acids, which also weakens you.
· Because when you stop this diet, you refabriquerez UNAVOIDABLY fat.
Slimming and regrossir
These diets high speed disrupt the hormonal system (leptin and ghrelin) that regulates your appetite and satiety and that imbalance hard after stop: you will still hungrier than before, so you eat more and you regrossirez (often at high speed too).
This type of plan does not change your old eating habits, just those who you are makes you fat.
Lose weight fast and become obese
Becoming obese, it is obviously a nightmare for followers of these RGV repeatedly, already obsessed with the idea of not going into a size 36.
Losing weight slowly and wisely
It is quite normal and often beneficial to evacuate really pounds.
For those installed during the winter, when we did the groundhog, it is often sufficient to move: they will not last long in regular attendance at a gym or a swimming pool.
Getting around by adopting but finally, and once and for all, a balanced diet with lots of vegetables at every meal, bread and / or cereal, fruit, drinking water and not sugary drinks in stalling its possible cravings with an apple or yogurt.
And taking the time to cook (without too much fat), which will make you money at the same time.
Also taking one to eat slowly, quietly, without a screen in front of me, but at the table with cutlery and small plates (one puts less!).
For thus you will walk your satiety center and eat less spontaneously.
Slowly but surely lose weight and once these habits finally taken, you do not get fatter.
Friday, March 20, 2015
Slim two is better!
Lose weight, when it is really necessary, is never an easy undertaking.
Whatever anyone says, it must show willingness and it feels most often alone (e) and outside of social and family life.
Thats why, two is always better.
Pounds torque
It was found that long married life had a tendency to be associated with weight gain more or less important. Some call it "the pounds of love"!
Is that we tend to celebrate Valentines Day several times a week, good food lovingly cooked by one or the other, and / or eating out.
To stay in bed more often: even if calorie consumption is therefore not negligible, it is still not the equivalent of what is spent where, single, we would trudge on a carpet in the room gym or take a bike ride with friends.
If it was thin before moving in with a partner, the gentlemen are comfortable tummy, buttocks and thighs ladies forcing them to change size of jeans and love handles are installed in both.
If it was already in trouble with her ideal weight, the situation is getting worse.
Deciding to lose weight
Comes a time when we fall asleep every night watching TV because of too hearty dinner and sometimes over-watered. And / or a day when the orgasmic conclusion of a WooHoo panting is impossible due to breathlessness.
It also has the annoyance of having to buy them from other pants, which may strain the budget and sets a bad mood. Especially since, in the register "the straw and the beam" eyes on the chubby nude each other are less tender.
And there may also have a medical examination whistling alert.
The decision is then required to lose weight.
It is easier to take in a gay couple, especially women, whereas in a traditional couple is usually Madam who introduced and will make sure to convince Sir, often more reluctant to the idea of put order in his diet.
But equality does not prevail in the energy balance of men and women. The former have higher expenses and they always lose weight faster. Thats why losing weight together is easier in a same-sex couple where the caloric needs of a (e) and both are virtually the same.
How to organize this weight loss?
It is not, of course, to get to a very restrictive diet necessarily unbalanced, which will lose weight at full speed. Because everyone then resume pounds in the following weeks and was no different, it will inevitably start falling in the downward spiral of yo-yo pounds.
It is simply to have a good breakfast with slices of wholemeal bread lightly buttered and possibly honey or jammy and implement balanced meals including lunch and dinner:
entry of cooked or raw vegetables.
a plate of lean meat or poultry or fish with vegetables and / or cereals: if he is not the latter, then we eat more bread.
a dairy, yogurt or cheese kind and, once or twice a week a bit of cheese.
fruit.
Turn it into drinking water and possibly a glass of wine.
This involves cooking, and with the least amount of fat.
We save time by setting all the menus for one week and allocating spots each, kitchen and shopping (with a specific list to avoid idle discussion then!).
And when we have lunch at the restaurant, we tell you what we ate and then we adapt the menu accordingly.
How to lose weight just two?
There is no way to count calories, weigh food and make apothecary style accounts "You, you are entitled to 150 grams of pulp and 100 g me."
You just serve everyone a small portion, possibly dessert plates, it can be funny.
And eat VERY SLOWLY, heads-lovers, no TV, no smartphone, no computer, no distractions, chewing well, paying attention to the tastes and flavors of what you absorb. Thus, the satiety center of each will have time to get under way (it takes 15-20 minutes) and everyone will stop eating when it has a fix and that his appetite will be conspicuously absent.
The menu is known, we keep a place for the dairy and fruit desserts and gentlemen possibly dig a new small portion of the dish as they need more energy. As for the ladies, they oblige themselves in any way to finish their plate if they have bitten off more than you can chew.
There remains because we have seen too by preparing the meals? They are put under vacuum or they are frozen and always a way to recycle them will be found.
Getting around two
It is also vitally important not to limit his caloric expenditure only to love exercise.
Rather than remain entwined on the couch watching TV, we go out after dinner and we will walk hand in hand. Each week one or two sessions of pool are programmed together.
This is also an opportunity to put themselves in a sport that is played in duo: tennis, badminton and / or buy a tandem.
Put away the balance
No need to weigh yourself every day.
Account for hundreds of lost of one or other programs can be a source of discouragement and / or destructive jealousy. Especially for ladies who lose weight still slower than gentlemen.
Thursday, March 19, 2015
May is Celiac Awareness Month and a call to action
UPDATED (5/5/11): The cake was built, and the FDA attended and released a statement. Please click here for the article, and for cake pictures.
THANK YOU. so very very much.Good morning! (or afternoon!)
I had the extreme pleasure of speaking and cooking this past weekend at the Gluten Free/Allergen Free Expo in Chicago. I made Carnitas and Country Captain Chicken (sans shrimp) for a group of wonderful people--many of whom are newly diagnosed with Celiac Disease.
Celiac Disease is an intolerance to gluten, which is found in wheat, barley, and rye.
We are a gluten free family. Many (maybe even most?) of my online and cookbook readers are NOT gluten free. In fact, I get an email pretty much daily from people who are unaware that my recipes are gluten free until they find out that either they (or a family member) needs to steer clear of gluten and they realize what my little notes mean.
My six year old has Celiac. I dont write about it very often, because its kind of a heavy subject, and I try to keep things light and upbeat here. But this is something that is a BIG PART of my life, and the lives of my family members.
My middle child was diagnosed with Celiac when she was 22 months old. She began vomiting sporadically, and continued to do so for about six months. We had recently moved back to the SF Bay Area, and I needed to go back to work. I was lucky enough to find a job teaching preschool where the kids (we had two at the time) could be with me.
But my little one didnt handle it well. She began getting sick, which I brushed off as her getting used to a childcare setting, and the germs (on a good day, I cut myself slack about this. on a bad day, I crumple in a heap and blame myself for her being sick. repeatedly.).
Fast forward to today, and she is perfect. The second our family went gluten free, she stopped vomiting. In fact, her immune system is now so strong that when a cold or flu goes through our home, she doesnt get it. Shes strong, healthy, and a fantastic gymnast and student.
I dont want her diet to define who she is. I want that to just be a tiny piece of who she is. Thats why I try my hardest to make sure that she has the same (if not better) food on hand for all of lifes occasions. School parties. Girl Scout events. The soccer team pizza party. Birthdays. Sleep overs.
So why am I telling you all this?
Because Id like your help.
There is a grassroots effort to get the FDA to regulate the labeling laws for gluten free products.
As of right now, there are no laws in place stating how many parts per million of gluten molecules can be present in food that has been labeled "gluten free."
There are no laws in place on how the food is handled, or a mandate to have a dedicated gluten free facility when packaging gluten free food.
There are no laws instructing restaurants how to properly prepare and serve food in restaurants that serve and advertise gluten free food.
Wed (Id) like that changed.
I have friends that cant eat packaged gluten free food. They get sick.
They get sick because the tiny bit of minute gluten left lurking in the food due to the manufacturing process is enough to set off a reaction.
That is not okay.
I have friends who have been hospitalized after eating at restaurants that ADVERTISE gluten free food.
That is not okay.
Gluten Free food should not be a fad. This is not a marketing ploy, or a way to "get in" on the next big food thing. This isnt the new vegan, or the new low-carb. Manufacturers should not be able to cash in on the "next big thing" in food without realizing that this is a life-or-death decision for MOST who have to strictly adhere to a gluten free diet.
Everyone should have safe food to eat.
If you can, I would greatly appreciate you taking the time to sign the online petition that will be presented to the FDA asking for proper regulation.
You do not need to give your home address, phone number, or other personal information. All that is asked is for your name and email address.
Please help spread the word.
Click here to sign the petition. The website is 1in133.org and tomorrow, May 4, there are a bunch of people assembling in Washington DC to prepare the worlds largest gluten free cake in an effort to help draw awareness to the campaign.
Im not going to be in DC. My girls need me home, but I will certainly do my part to help however I can. You can help, too.
thank you for sticking around, and for your support, kindness, and understanding. Ill be back in a bit with your regularly scheduled crockpot recipe.
xoox steph
Monday, March 16, 2015
Health and Heparan Sulfate Circulation — Connective Tissue is Alive
--- The other 200 posts are here ---
Arthritis, Alzheimer’s, diabetes, cardiovascular disease, osteoporosis, cancer, etc. are all diseases of cellular metabolism and secretion. What goes on inside cells and on their surfaces explains a lot about health and why we get sick. Cells feed off of what’s around them, use some of those materials to replicate and package up cell-made materials for export. Eat, replicate and secrete. Symptoms of disease result if those processes are compromised.
Cell that make Cartilage, Eat CartilageThe connective tissue that makes up the cartilage of tendons and the non-mineral parts of bones, as well as a layers of skin, is made up of proteins (collagen) and polysaccharides (glycosaminoglycans, GAGs), e.g. heparan sulfate, hyaluronan and chondroitin sulfate, produced by chondrocytes or fibroblasts. These proteins and polysaccharides are synthesized and then secreted by cells. This process goes on continuously, since the connective tissue is alive and literally crawling with cells that make the cartilage. To keep the connective tissue healthy, the old tissue has to be digested, so that new material can replace it. Thus, the cells that live in cartilage also eat cartilage. These cells get all of their nutrients, e.g. protein and carbs, from eating cartilage. They don’t get glucose and amino acids, or even oxygen (they ferment), from the blood, because there are no blood vessels in cartilage. The photomicrograph at left shows the red chondrocytes surrounded by a light capsule of heparan sulfate as they burrow through the purple cartilage. The next micrograph shows the cytoskeleton of actin filaments (stained with a red fluorescent dye, that lies under the cytoplasm of a chondrocyte. Motor proteins move other proteins, such as syndecans, the proteins to which the heparan sulfate chains are attached, through the cell membrane (see the animations below.) The last micrograph shows the green stained microtubule network on which vesicles move to carry heparan sulfate products from one end of the cell to the other (under the actin and past the orange-dyed nucleus) during synthesis and digestion.
Chondrocytes Burrow Through CartilageChondrocytes are the cells that eat and make cartilage, but all of this eating and making goes on at the same time that the cartilage is also holding everything together, i.e. it is still strong. If cartilage is cut and the cut ends are held tightly together, the chondrocytes will knit the cartilage together and it will become as strong as it was.
Heparan Sulfate Circulates over the Surface of Cells
Chondrocytes are not actually rigidly embedded in the cartilage, but rather maintain a capsule of heparan sulfate around themselves. Thus, they continue to secrete a mixture of heparan sulfate, chondroitin sulfate and collagen, but the heparan sulfate is recycled through the capsule and the other molecules merge into the existing cartilage. Thus, the heparan sulfate is a kind of carrier that keeps the cartilage from “setting up” while it is being made and transported. Other cells of the body, such as neurons, don’t make cartilage, but they still have heparan sulfate (HS) circulation that is intimately involved in many other processes, such as the action of hormones. Disruption of HS circulation causes the symptoms of Alzheimer’s or type 1 diabetes, for example, since amyloids assemble as filaments on threads of HS, and the amyloid filaments jam essential HS circulation. Plaque in atherosclerotic vessels is high in HS content. HS is also a major component surrounding vessels to form the blood brain barrier and the barrier to protein loss from kidneys into urine or loss into the gut lumin. Heparin (fragments of HS) is continually released from mast cells in the lining of the gut to prevent pathogens from binding to cell HSPGs.
HS Sweep the Cell Surface
There is a constant flow of heparan sulfate proteoglycans (HSPGs) through the cell membrane from the rear of the chondrocyte to the front where the HS is digested again and the protein that was embedded in the membrane, syndecan, is recycled to the Golgi for another trip. HSPGs (animation to left with blue protein and yellow HS) are attached to motor proteins that propel them through the membrane along microfilaments of actin that form the cyctoskeleton just under the membrane in the cortical region of the cell. Thus, the heparan sulfate of the HSPGs stick out like hair from the cell surface and sweep continuously from the back to the front of the cell. At the front of the cell, the HS sweeps through the intact cartilage and reverses the process of cartilage assembly. The chondroitin sulfate, collagen and HSPGs are dragged into the cell and digested. The protein parts of the HSPGs are transported to the Golgi and the HS is synthesized along with other cartilage components and moved in vesicles along microtubules before it is secreted.
HS is Secreted at One End and Eaten at the Other
The animation left shows 1) the initial digestion of the cartilage proteins and polysaccharides on the left. These cartilage components of amino acids and sugars, are used by the chondrocytes as their sole nutrients 2), and to produce new proteoglycans 3) HS and chondroitin sulfate proteoglycans, in the Golgi, are 4) packaged into secretory vesicles and are 5) secreted on the right. The HS chains, attached to proteins, are 6) swept through the membrane (see the first animation above) toward the front of the cell, leaving the collagen and chondroitin sulfate for form cartilage behind. In the process, the heparan sulfate proteoglycans 7) disrupt and solublilize old cartilage ahead as the chondrocytes 8) move through the connective tissue like moles digging through soil.
Other Cell Processes Involving Heparan Sulfate:
- Amyloids of Alzheimer’s and type I diabetes assemble bound to HS.
- Hormones bind to receptors wrapped around HS.
- Blood clotting is controlled by HS.
- Complement is controlled by HS.
- Blood brain barrier is composed of HS.
- Kidney protein barrier is composed of HS.
- Inflammation blocks HS synthesis and promotes heparanase synthesis.
- GAGs are animal soluble fiber when eaten and feed gut flora.
- Pathogens bind to HS.
- HIV-TAT is transported between cells by HS circulation.
- Heparin is made by heparanase fragmentation of HSPG in mast cells and is secreted along with histamine.
- NFkB activation inhibits HSPG production and stimulates heparanase production.
- Heparan sulfate proteoglycans organize nerve synapses and acetylcholine esterase binds to HS.
- Gastric proteases cleave around heparin binding domains of proteins, e.g. milk, consist of clusters of basic amino acids. Peptides with heparin binding domain are antimicrobial; all of the heparin binding peptides are subsequently degraded by pancreatic proteases.
- Heparanase is initially secreted inactive and bound to HSPGs, but it remains bound and is internalized again along with the recycling HSPGs, and is activated before being secreted again.
- Allergens and autoantigens are unusual proteins with sequences of three adjacent basic amino acids (arginine or lysine) that require HSPG circulation for presentation of the immune system. Nuclear proteins that interact with nucleic acids have sequences of four basic amino acids, the nuclear translocation signal, and are therefore common antinuclear auto antigens.
Health Diagrams
Saturday, March 14, 2015
Easy Is Starving A Good Way To Lose Weight Reviews
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Is Starving A Good Way To Lose Weight This is explained due to the fact a number of supplements that happen to be natural could turn out becoming a dangerous part of some sort of weight reduction diet regime. Some organic and natural preparations havent been considered simply by FDA or other specialists as well as some have shown to be debilitating to mention the bare minimum. Care is essential when utilizing a natural supplement together with a fat loss diet program. Employ common sense when coping with these kind of supplements and also carry Just seeing that led on the container as well as as prescribed by a doctor. Herbal supplements as soon as utilised poorly may lead to condition along with death for any person.
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Diet Meat What is the diet meat of the flesh
Seeking information to start a new diet meat and lose weight fast? It is believed that the diet meat achieves this goal. Like many other diet plans, diet has its advantages and disadvantages. Lets see how and why this special diet meat can help you lose a few kilos in a few days.
Diet meat and satiety
Several scientific studies have shown that a diet meat rich in protein can reduce appetite and therefore help someone lose weight. Scientists believe that a high level of protein in the blood may be able to prevent the appetite stimulating hormones play a role.
Diet meat and Metabolism
Meat is rich in vitamin B. Vitamin B complex and weight loss go hand in hand. Do you know why? B vitamins are able to accelerate the bodys metabolism. diet meat, such as lean beef, pork and chicken is a major dietary source of B-complex vitamins.
What is the diet meat of the flesh?
1) Eat more meat. Your daily intake of protein should represent 30% of total calories. White meat is preferred. Try to choose lean cuts of meat in diet in fat.
2) Eat 50% fewer carbs like whole grains, legumes, vegetables and fruits. Do not eat white bread, white rice, and pastries.
3) Reduce fat intake to 20% of daily energy intake.
4) Eat smaller meals. They are allowed to have snacks between meals when you feel a little hungry.
5) Get more exercise!
Disadvantages meat in diet
1) The diet meat is rich in fatty acids of the fat, particularly saturated and cholesterol. It is believed that foods containing a high proportion of saturated fatty acids raise blood cholesterol and cause heart disease.
2) A high intake of meat in diet leads to excess uric acid can cause various diseases such as gout, rheumatism and kidney stones.
3) Almost all commercial meat is contaminated in some way by toxins, bacteria and chemicals such as hormones and growth of synthetic nitrates, which can profoundly affect our health and wellbeing.
4) Some clinical studies have shown that people who regularly eat red meat have a higher risk of colon cancer.
5) Consumption of processed meats, such as pork, beef or lamb, can significantly increase the rate of prostate cancer in men of different ages.
6) Scientists have also found that women whose diet was rich in meat, such as beef or ham are more likely to develop endometriosis.
Monday, March 9, 2015
Abdominal obesity is the biggest enemy of your health! life diets
Abdominal obesity is the biggest enemy of your health!
Abdominal obesity appears in two different forms. The first figure is the fat under the skin. The second is fat guts. They are found around the internal organs, which is the real enemy of health!
Thursday, May 2, 2013 fight against abdominal obesity
Abdominal obesity and health
How much should be weighed, Doctor? Its a common question, an important question. It is common because two-thirds of Americans weigh more than what should be their weight. It is important because excess weight goes to what is beyond the distortion of body shape. fats:
Responsible for high levels of cholesterol low-density proteins ("harmful") and triglycerides.
Reduce cholesterol high-density proteins ("good") at the same time.
Disruption of the bodys response to insulin, which leads to higher levels of blood sugar and insulin.
Contribute to the major causes of death and disability, including heart attacks, strokes, high blood pressure, cancer, diabetes and inflammation osteoarthritis, fatty liver and depression.
Responsible for approximately 1,000 deaths in the United States every day.
Given these risks, it is not surprising that you want to find out how much should be weight. But this question is common and what is important is in fact the wrong question. For health, the problem is not in how much is your weight, but in the level of abdominal obesity that you have.
Increase the size of the abdomen
During the past few years, attracted a number of studies of attention to the importance of abdominal obesity. Some research showed that abdominal obesity is a predictor of danger factor, more than body mass index (BMI).
For example, a study in 2008 conducted on 245 533 dollars that large waist circumference was associated with an increased mortality rate, even in people who have a normal body mass index (BMI). Another study showed the 2,229 victims of heart attacks that patients with large waist circumference had a higher rate of death, so that they have a low body mass index (BMI).
Deficiencies in body mass index (BMI)
Although the body mass index (BMI) is the official standard, but has several disadvantages.
Athletes professional people with big muscles and a few body fat can have a body mass index (BMI) of up to 32.
Perhaps BMI fails in that accurately reflects the level of body fat in adults who have lost a basic amounts of muscle.
The most important problem is that BMI reflects the level of total fat in the body without considering how to distribute these fats. Although there was no increase fat good, but the increase in abdominal fat is the worst case.
What makes abdominal obesity is very harmful? Scientists do not know why is certain, but new research offers important interpretations.
Abdominal obesity appears in two different forms. The first picture is of fat under the skin, which is located just under the skin. These fats behave the same fat found everywhere in the body. Its not friendly to your health, but it is not a source of danger particularly well. The second type is fat guts. They are found around the internal organs, which is the real enemy of health. Why?
Interpretations of early the entrails obesity was associated with excess activity of the bodys response to the pressure, making it produces large amounts of stress hormones, such as adrenaline and cortisol.
There latest interpretation says that the entrails fat cells release their metabolic products directly into the blood that goes directly to the liver. As a result, the entrails fat cells that grow and are filled Balglsaredat triple pour excess free fatty acids in the liver (all fat is made up of free fatty acids). And this can be toxic to the liver. And free fatty acids accumulate also in the pancreas, heart and other organs, where it caused damage.
A third theory shows the complex nature of the fatty cells. The scientists believe that fat cells are just a place to store excess calories in the form of fat. But it is now clear that in addition to storing excess energy, fat cells produce a large number of proteins that enter the bloodstream and affect other organs. Some of these proteins leads to damage, and others can be protective. And entrails fat cells produce many harmful substances, with a little bit of useful material.
Measurement of abdominal obesity
The most accurate way to measure obesity entrails are imaging computed tomography (CT) or magnetic resonance imaging (MRI). However, the much easier way is to determine the ratio of waist to hip circumference. But many experts have turned up to a simpler method: measuring waist circumference.
To measure your waist circumference properly, you need a tape measure clothing stainless stretchable, not metal measuring tape drive.
GIVE your shoes stop with the put your feet next to each other.
Make sure to have your belly naked. Relax and exit . Not Pull exhalation the belly inward, it may give you better figure but will not improve your health. And the use of belt size instead is unrealistic.
Measure the circumference of your waist at the navel. And make sure you make the tape parallel to the ground. And record the measurement in inches with rounding to the nearest ten, and then repeat the measurement to make sure you are set correctly.
Check the table below to know what means the circumference of your waist for your health.
Waist circumference control
So, what can you do to reduce your waist circumference? You must forget the tummy tuck. Its good to increase the strength of the abdominal muscles, which may improve your health, but it does not burn abdominal obesity are optional. Tools that are reducing the fat is the worst, too, because they waste time and money without the lead to reduce the circumference of your waist.
You must forget liposuction. That surgery can remove fat under the skin of your torso, but not fat guts. Cosmetic surgery will improve your appearance and reduce your waist circumference, but will do nothing for the metabolism in your body will benefit your health.
Remember basic things. The only way to reduce the fat guts are losing weight, and burn more calories - by exercise - so that the amount of burning more calories that are ingested through food. Continuous weight loss requires reducing calories while increasing exercise. Here are some tips:
Reduce the amount of food in your meals.
Choose your wisely foods. And avoiding foods high in sugar and / or fat. It is caloric-ally dense, and slip into your stomach very easily. Instead, eat fruits and vegetables and whole grain products. Its high dietary fiber, and you need a longer time to eat, and probably Chbek more. Piece of chocolate, medium-sized and medium-sized apple, both of which contain about 100 calories (if already medium-sized). Now the thought of eating 5 pieces or 5 apples. It is clear that most people can easily eat the pieces, however, only few can finish eating all five apples.
Exercise more from the exercise. Walking two miles a day will significantly reduce the risk of heart disease, stroke, diabetes, high blood pressure and early death. It will also burn calories. The man who weighs 200 pounds will be used about 220 calories in 30 to 40 minutes of brisk walking. That alone means the loss of about 30 pounds in one year - without any nutritional changes. The exercises also help in maintaining weight loss, unlike popular diets significantly. Secondly, it will burn excess abdominal fat, which is the thing that never does a tummy tuck and ways to reduce fat in certain areas.
In order to lose weight fast, each less and exercises more.
Male body shape
Abdominal obesity has many other names, including obesity, the upper part of the body, stem obesity and central obesity and obesity entrails. In terms of more versatile, also known as the belly of cola and shape of the apple and alternative cupboard. And thats where this type of fat distribution more common in males than in females, perhaps known as the male body shape.
According to the name, abdominal obesity is a form of risk - and abdominal obesity are increasing even faster than the body mass index (BMI) in our society. But by using a simple program of diet and exercise, can men with apple shape to lose weight. If you change the the "alternative Dolapk" will maintain your health.
Read more in Medicine Web site: abdominal obesity is the biggest enemy of your health!
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Sunday, March 8, 2015
How important is sleep
Sleep is essentialfor those who want to live healthy. We spend more than a third of our lives sleeping and the quality of the latter, directly affect our quality of life.Quality sleep allows long-term preservation of our health, but also short-term recovery of the previous day and build enough energy for the next.
So, sleep well is a sure bet like the short term.
so how important is sleep?
The importance of sleep for health
the importance of sleep onhealth is well documented and we know that an important function as:
1. Growth
2. Brain maturation
3. The development and preservationof our cognitive capacities
4. The temperature control
5. Adjusting many hormonal secretions
A lack of sleep or poor quality sleep can have a real impact onhealth and the proper conduct of everyday life.
the importance of sleep onhealth is well documented and we know that an important function as:
1. Growth
2. Brain maturation
3. The development and preservationof our cognitive capacities
4. The temperature control
5. Adjusting many hormonal secretions
A lack of sleep or poor quality sleep can have a real impact onhealth and the proper conduct of everyday life.
Why we have to know how important is sleep.
Lack of sleep increases the risk:
1. Sleepiness
2. Weight gain and obesity
3. Stress
4. Depression
5. Cardiovascular diseases
6. Concentration disorders
7. Diabetes etc. ...
Lack of sleep increases the risk:
1. Sleepiness
2. Weight gain and obesity
3. Stress
4. Depression
5. Cardiovascular diseases
6. Concentration disorders
7. Diabetes etc. ...
The above list is not exhaustive and the negative effects of sleep deprivation are too numerous to be listed.
To know how important is sleep, isessential for health and good sleep is to put all the advantages on his side to preserve it.
To know how important is sleep, isessential for health and good sleep is to put all the advantages on his side to preserve it.
Daily injection which is better than dieting or exercise on NHS soon
A treatment of injections that can help people lose a stone more than they normally would by dieting or exercising more has been approved by health watchdogs.
Liraglutide, which has been described by doctors as life-changing, could be available on prescription in months.
Slimmers typically lose almost a stone more than they would by simply watching how many calories they consume and doing more exercise.
Trials showed that some severely obese patients lost so much weight they were able to abandon their wheelchairs and walk normally for the first time in years.
Liraglutide also lowers blood pressure, raises good cholesterol and prevents diabetes.
According to its makers, Novo Nordisk of Denmark, the drug even produces a feel-good factor, making dieting a pleasure.
But some experts have already warned it does not provide a long-term solution to the growing problem of obesity in Britain.
Novo Nordisk will apply for it to be prescribed on the NHS after Friday’s ruling by the European drugs regulator that it is safe and effective.
There are fears however that Nice – Britain’s drugs rationing body – will judge it too expensive for routine use on the NHS.
Liraglutide costs from £2.25 a day, which is roughly double the price of Orlistat, the only other prescription diet drug.
Patients inject the drug into their stomach before breakfast every day. It works by suppressing appetite.
Liraglutide, which will be given the brand name Saxenda, is already used at a lower dose to treat diabetes. It is based on a hormone found in the gut and sends signals to the brain that trick it into feeling full.
As a result, people eat 10 per cent less food than normal.
Trials of Liraglutide found that men and women who injected themselves daily lost an average of 19lb in 12 months. This is almost a stone more than they would lose by being on a diet and increasing the amount they exercise.
Furthermore one third or those who took part in the trials shed 23lb – more than a stone and a half. For a 14 stone woman that kind of weight loss would usually mean dropping two dress sizes.
The drug which, like insulin, comes in an injectable pen, also has such a significant effect on blood pressure that patients can dispense with the drugs they use to keep it under control.
Like Orlistat, its prescription is likely to be limited to those who are obese or who are overweight and have another health problem such as high blood pressure.
Mike Lean, professor of human nutrition at Glasgow University, told the Mail: "Liraglutide is absolutely life-changing for many of our most difficult-to-manage patients. Most do well, and some amazingly well. And it is extraordinarily safe, at least over the two to three years for which we have good evidence, with no signals to suggest serious side-effects.
"The only real downside is that it is jolly expensive."
Professor Jason Halford, former president of the UK Association for the Study of Obesity, said: "It is potentially very exciting. The real benefit of it is that it is targeting appetite. It strengthens the effects of satiety."
Obesity levels have doubled over the past two decades, making the UK the second-fattest nation in Europe.
Exptensive research has found that being obese can lessen persons lifespan by as much as nine years and raise the risk of a host of health problems including diabetes, heart disease, stroke and cancer.
Tests have shown that dieters taking liraglutide lose almost twice as much weight as those on Orlistat.
However, Professor Iain Broom, director of the Centre for Obesity Research at Robert Gordon University in Aberdeen, said that drugs were never going to provide a long term answer to obesity.
He said: "Until society changes and the Government’s relationship with the food industry changes and the food industry itself changes, we are not going to get anywhere very fast."
The European Commission is expected to approve the drug’s licence within the next two months, paving the way for it to go on sale. Novo Nordisk says it could be launched in Europe, including the UK, this year.
By Patrick Sawer
Source: http://www.telegraph.co.uk/lifestyle/wellbeing/dietandfitness/11367203/Daily-injection-which-is-better-than-dieting-or-exercise-on-NHS-soon.html
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